Peptide detail

AOD-9604

AOD-9604 is a modified fragment of human growth hormone (hGH) that retains the fat-burning effects of hGH without its growth-promoting or diabetogenic effects. Specifically, it's derived from the C-terminus of hGH (amino acids 176-191), the region responsible for its lipolytic (fat-burning) activity. AOD-9604 works by mimicking how natural growth hormone regulates fat metabolism but without affecting blood sugar or growth. It stimulates lipolysis (the breakdown of fat), inhibits lipogenesis (the formation of fat), and can regulate fat metabolism through pituitary mechanisms. The peptide has been shown to specifically target adipose (fat) tissue, particularly abnormal fat accumulation, and may stimulate fat release from adipocytes (fat cells) while enhancing thermogenesis to burn released fat as energy. Original research focused on obesity treatment, but it's also gaining interest for body composition management, anti-aging applications, and potentially for cartilage and bone regeneration.